I always take it as a good sign when people start complaining about the colours in a site design. If that’s all they can find to comment on, then more-or-less everything else must be pretty much ready to go.
You can never please everybody. Although, as Kathy Sierra points out, you can easily please nobody (actually she’s been talking about this for a while now). Sometimes you just have to go with what you think is right. And, when you do get opinions from others make sure you’re watching what they do rather than listening to what they say.